Prevalence of Glucose-6-Phosphate Dehydrogenase Deficiency among Neonates with Severe Neonatal Hyperbilirubinemia: A Cross-Sectional Study from Assam

Abstract

Background Hyperbilirubinemia is a common issue in neonates, with jaundice affecting a significant proportion of both term and preterm infants. While most cases of neonatal jaundice are benign, a subset requires intervention. Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a notable cause of pathological jaundice that can lead to severe hyperbilirubinemia and neurological complications. So, this study aimed to determine the prevalence of G6PD deficiency among neonates with severe hyperbilirubinemia.

Keywords

• G6PD deficiency, Hyperbilirubinemia, Neonatal jaundice, Severe hyperbilirubinemia, Prevalence