A small bacteriophage protein determines the hierarchy over co-residential jumbo phage in Bacillus thuringiensis serovar israelensis

Anja Pavlin; Anže Lovše; Gregor Bajc; Jan Otoničar; Amela Kujović; Živa Lengar; Ion Gutierrez-Aguirre; Rok Kostanjšek; Janez Konc; Nadine Fornelos; Matej Butala

doi:10.1038/s42003-022-04238-3

Communications Biology (Nov 2022)

A small bacteriophage protein determines the hierarchy over co-residential jumbo phage in Bacillus thuringiensis serovar israelensis

Anja Pavlin,
Anže Lovše,
Gregor Bajc,
Jan Otoničar,
Amela Kujović,
Živa Lengar,
Ion Gutierrez-Aguirre,
Rok Kostanjšek,
Janez Konc,
Nadine Fornelos,
Matej Butala

Affiliations

Anja Pavlin: Department of Biology, Biotechnical Faculty, University of Ljubljana
Anže Lovše: Department of Biology, Biotechnical Faculty, University of Ljubljana
Gregor Bajc: Department of Biology, Biotechnical Faculty, University of Ljubljana
Jan Otoničar: Department of Biology, Biotechnical Faculty, University of Ljubljana
Amela Kujović: Department of Biology, Biotechnical Faculty, University of Ljubljana
Živa Lengar: Department of Biotechnology and Systems Biology, National Institute of Biology
Ion Gutierrez-Aguirre: Department of Biotechnology and Systems Biology, National Institute of Biology
Rok Kostanjšek: Department of Biology, Biotechnical Faculty, University of Ljubljana
Janez Konc: Theory Department, National Institute of Chemistry
Nadine Fornelos: Broad Institute of MIT and Harvard
Matej Butala: Department of Biology, Biotechnical Faculty, University of Ljubljana

DOI: https://doi.org/10.1038/s42003-022-04238-3
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 12

Abstract

Read online

Insights are provided into the action of gp7, a small protein encoded by the bacteriophage GIL01 in the biopesticide Bacillus thuringiensis serovar israelensis. Gp7 1 hinders the induction of cohabiting prophage pBtic235 and downregulates its genes in a complex with host LexA in stressed cells.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal