Nature Communications (Sep 2019)

Production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories

  • Christian Bille Jendresen,
  • Alex Toftgaard Nielsen

DOI
https://doi.org/10.1038/s41467-019-12022-x
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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Toxicity and limited solubility inhibits the biological production of many organic compounds. Here the authors metabolically engineer sulfate uptake and activation in order to produce sulfate esters of phenolic compounds, such as zosteric acid, thereby addressing these issues.