Orbital: The Electronic Journal of Chemistry (Oct 2014)
Electroanalytical Determination of Danofloxacin in Biological Samples Using Square Wave Voltammetry
Abstract
The voltammetric behavior of danofloxacin (DFX) has been studied, in aqueous solution, on a glassy carbon electrode using square wave voltammetry (SWV) as electroanalytical technique. After optimization of the experimental conditions, DFX was analyzed in spiked biologic samples using a Britton-Robinson buffer with pH = 5.0 as the supporting electrolyte. Oxidation occurs at 0.98 V vs. Ag/AgCl in a two-electron process controlled by adsorption of the electrogenerated products on the electrode surface. A acceptable recovery was obtained for assay of spiked biologic samples, with value of 98.7% for the swine urine and 95.3 % for the bovine urine.
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