Synthesis, Antifungal Ergosterol Inhibition, Antibiofilm Activities, and Molecular Docking on β‑Tubulin and Sterol 14-Alpha Demethylase along with DFT-Based Quantum Mechanical Calculation of Pyrazole Containing Fused Pyridine–Pyrimidine Derivatives

• Nisheeth C. Desai,
• Ashvinkumar G. Khasiya,
• Dharmpalsinh J. Jadeja,
• Jahnvi D. Monapara,
• Aratiba M. Jethawa,
• Bharti P. Dave,
• Sree Kanth Sivan,
• Vijjulatha Manga,
• Pravin C. Mhaske,
• Doongar R. Chaudhary

Affiliations

Nisheeth C. Desai

Division of Medicinal Chemistry, Department of Chemistry, Mahatma Gandhi Campus, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar, Gujarat, India

Ashvinkumar G. Khasiya

Division of Medicinal Chemistry, Department of Chemistry, Mahatma Gandhi Campus, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar, Gujarat, India

Dharmpalsinh J. Jadeja

Division of Medicinal Chemistry, Department of Chemistry, Mahatma Gandhi Campus, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar, Gujarat, India

Jahnvi D. Monapara

Division of Medicinal Chemistry, Department of Chemistry, Mahatma Gandhi Campus, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar, Gujarat, India

Aratiba M. Jethawa

Division of Medicinal Chemistry, Department of Chemistry, Mahatma Gandhi Campus, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar, Gujarat, India

Bharti P. Dave

School of Science, Indrashil University, Rajpur, Gujarat, India

Sree Kanth Sivan

Department of Chemistry, University College for Women, Osmania University, Hyderabad, India

Vijjulatha Manga

Department of Chemistry, University College for Women, Osmania University, Hyderabad, India

Pravin C. Mhaske

Post-Graduate Department of Chemistry, S. P. Mandali’s Sir Parashurambhau College, Pune, Maharashtra, India

Doongar R. Chaudhary

CSIR-Central Salt and Marine Chemicals Research Institute, Bhavnagar, Gujarat, India