Device Closure of Hemodynamically Significant Patent Ductus Arteriosus in Premature Infants

Alban-Elouen Baruteau, MD, PhD; Mathilde Méot, MD; Nadir Benbrik, MD; Céline Grunenwald, MD; Naychi Lwin, MD; Juliana Patkai, MD; Jean-Christophe Rozé, MD; Damien Bonnet, MD, PhD; Sophie Malekzadeh-Milani, MD

JACC: Advances (Oct 2024)

Device Closure of Hemodynamically Significant Patent Ductus Arteriosus in Premature Infants

Alban-Elouen Baruteau, MD, PhD,
Mathilde Méot, MD,
Nadir Benbrik, MD,
Céline Grunenwald, MD,
Naychi Lwin, MD,
Juliana Patkai, MD,
Jean-Christophe Rozé, MD,
Damien Bonnet, MD, PhD,
Sophie Malekzadeh-Milani, MD

Affiliations

Alban-Elouen Baruteau, MD, PhD: Department of Pediatric Cardiology and Pediatric Cardiac Surgery, Nantes Université, CHU Nantes, FHU PreciCare, Nantes, France; Nantes Université, CHU Nantes, INSERM, CIC FEA 1413, Nantes, France; Nantes Université, CHU Nantes, CNRS, INSERM, l’institut du thorax, Nantes, France; Nantes Université, INRAE, UMR 1280, PhAN, Nantes, France; Address for correspondence: Dr Alban-Elouen Baruteau, Service Médico-chirurgical de Cardiologie Pédiatrique, Centre Hospitalier Universitaire de Nantes, 7 Quai Moncousu, 44093 Nantes Cedex 01, Nantes, France.
Mathilde Méot, MD: M3C-Necker, Department of Pediatric and Congenital Cardiology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France
Nadir Benbrik, MD: Department of Pediatric Cardiology and Pediatric Cardiac Surgery, Nantes Université, CHU Nantes, FHU PreciCare, Nantes, France
Céline Grunenwald, MD: Department of Pediatric Cardiology and Pediatric Cardiac Surgery, Nantes Université, CHU Nantes, FHU PreciCare, Nantes, France
Naychi Lwin, MD: Department of Pediatric Cardiology and Pediatric Cardiac Surgery, Nantes Université, CHU Nantes, FHU PreciCare, Nantes, France; Nantes Université, CHU Nantes, INSERM, CIC FEA 1413, Nantes, France
Juliana Patkai, MD: Department of Neonatal Medicine, Cochin-Port Royal Hospital, FHU PREMA, APHP, Paris, France
Jean-Christophe Rozé, MD: Nantes Université, CHU Nantes, INSERM, CIC FEA 1413, Nantes, France
Damien Bonnet, MD, PhD: M3C-Necker, Department of Pediatric and Congenital Cardiology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; University Paris Cité, Paris, France
Sophie Malekzadeh-Milani, MD: M3C-Necker, Department of Pediatric and Congenital Cardiology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France

Journal volume & issue: Vol. 3, no. 10
p. 101211

Abstract

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The patent ductus arteriosus is a very common condition in preterm infants, and a hemodynamically significant patent ductus arteriosus increases morbidity and mortality in these vulnerable patients. However, despite numerous randomized controlled trials, there is no consensus regarding management. Medical therapy is typically offered as first-line treatment, although it yields limited success and carries the potential for severe adverse events. In recent years, there has been rapid development in transcatheter patent ductus arteriosus closure primary with the use of the Amplatzer Piccolo Occluder, and this has gained widespread acceptance as a safe and effective alternative to surgical ligation in extremely low-birth-weight infants weighing over 700 g. This article aims to provide an appraisal of the patient selection process, a step-by-step procedural guide, and a comprehensive review of the outcomes associated with this approach.

Published in JACC: Advances

ISSN: 2772-963X (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid
Website: https://www.sciencedirect.com/journal/jacc-advances

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