Evaluation of the impact of nasal colonization with methicillin-resistant Staphylococcus aureus on left ventricular assist device infections

Lauren J. Koscal; Holly Meadows; Brian R. Raux; Krutika N. Mediwala; Erin Weeda; Brian Houston; Deeksha Jandhyala; Jaclyn M. Hawn

doi:10.1017/ash.2022.46

Antimicrobial Stewardship & Healthcare Epidemiology (Jan 2022)

Evaluation of the impact of nasal colonization with methicillin-resistant Staphylococcus aureus on left ventricular assist device infections

Lauren J. Koscal,
Holly Meadows,
Brian R. Raux,
Krutika N. Mediwala,
Erin Weeda,
Brian Houston,
Deeksha Jandhyala,
Jaclyn M. Hawn

Affiliations

Lauren J. Koscal: ORCiD; Department of Pharmacy, University of Florida Health at Jacksonville, Jacksonville, Florida
Holly Meadows: Department of Pharmacy, Medical University of South Carolina, Charleston, South Carolina
Brian R. Raux: Department of Pharmacy, Medical University of South Carolina, Charleston, South Carolina
Krutika N. Mediwala: ORCiD; Department of Pharmacy, Medical University of South Carolina, Charleston, South Carolina
Erin Weeda: ORCiD; Medical University of South Carolina, College of Pharmacy, Charleston, South Carolina
Brian Houston: ORCiD; Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina
Deeksha Jandhyala: Division of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina
Jaclyn M. Hawn: ORCiD; Department of Pharmacy, Medical University of South Carolina, Charleston, South Carolina

DOI: https://doi.org/10.1017/ash.2022.46
Journal volume & issue: Vol. 2

Abstract

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In this retrospective cohort study, we evaluated the predictive value of methicillin-resistant Staphylococcus aureus (MRSA) nasal swabs for the development of MRSA infections in patients with left ventricular assist devices. In 106 patients, the MRSA nasal swab had a negative predictive value of 92.9% demonstrating a potential role in antibiotic de-escalation.

Published in Antimicrobial Stewardship & Healthcare Epidemiology

ISSN: 2732-494X (Online)
Publisher: Cambridge University Press
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Medicine: Public aspects of medicine
Website: https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology

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