Журнал инфектологии (Apr 2022)

Influence of specific prevention on the infectious activity of the virus tick-borne encephalitis (review of own research)

  • G. N. Leonova

DOI
https://doi.org/10.22625/2072-6732-2022-14-1-43-52
Journal volume & issue
Vol. 14, no. 1
pp. 43 – 52

Abstract

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The results of our own long-term research on the effectiveness of specific prevention of viral infectious diseases using the example of tick-borne encephalitis are presented in the article. The peculiarities of the formation of the immune response during vaccination against tick-borne encephalitis are shown on the model of the vaccine preparation «Encepur® adult» (Germany). The terms of revaccination were substantiated, taking into account the ELISA parameters of the immunity intensity to the tick-borne encephalitis virus, equal to not less than 1: 400. The experiment shows the mechanisms of passive immunization of persons infected with the tick-borne encephalitis virus, based on the protective effect of specific antibodies. The established high level of immune protection during complex vaccination with drugs against tick-borne encephalitis from different manufacturers helps to understand its effectiveness in relation to vaccination against other infections.

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