Nature Communications (Jun 2018)

Single-walled carbon-nanohorns improve biocompatibility over nanotubes by triggering less protein-initiated pyroptosis and apoptosis in macrophages

  • Bing He,
  • Yujie Shi,
  • Yanqin Liang,
  • Anpu Yang,
  • Zhipu Fan,
  • Lan Yuan,
  • Xiajuan Zou,
  • Xin Chang,
  • Hua Zhang,
  • Xueqing Wang,
  • Wenbin Dai,
  • Yiguang Wang,
  • Qiang Zhang

DOI
https://doi.org/10.1038/s41467-018-04700-z
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 21

Abstract

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Carbon-nanohorns have a unique morphology and structure yet little is known about the biocompatibility. Here, the authors investigate the biocompatibility and bio-interaction of carbon nanohorns, compare them to carbon nanotubes and show the superior biocompatibility and safety of the nanohorns.