Frontiers in Medicine (Jan 2024)
The relationships between lens diameter and ocular biometric parameters: an ultrasound biomicroscopy-based study
- Zhiqian Huang,
- Zhiqian Huang,
- Zhiqian Huang,
- Zhiqian Huang,
- Zhiqian Huang,
- Jiao Qi,
- Jiao Qi,
- Jiao Qi,
- Jiao Qi,
- Jiao Qi,
- Kaiwen Cheng,
- Kaiwen Cheng,
- Kaiwen Cheng,
- Kaiwen Cheng,
- Kaiwen Cheng,
- Shuyu Liu,
- Shuyu Liu,
- Shuyu Liu,
- Shuyu Liu,
- Shuyu Liu,
- Keke Zhang,
- Keke Zhang,
- Keke Zhang,
- Keke Zhang,
- Keke Zhang,
- Yu Du,
- Yu Du,
- Yu Du,
- Yu Du,
- Yu Du,
- Yi Lu,
- Yi Lu,
- Yi Lu,
- Yi Lu,
- Yi Lu,
- Xiangjia Zhu,
- Xiangjia Zhu,
- Xiangjia Zhu,
- Xiangjia Zhu,
- Xiangjia Zhu
Affiliations
- Zhiqian Huang
- Department of Ophthalmology, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Zhiqian Huang
- Eye Institute, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Zhiqian Huang
- NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Zhiqian Huang
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Zhiqian Huang
- State Key Laboratory of Medical Neurobiology, Shanghai, China
- Jiao Qi
- Department of Ophthalmology, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Jiao Qi
- Eye Institute, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Jiao Qi
- NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Jiao Qi
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Jiao Qi
- State Key Laboratory of Medical Neurobiology, Shanghai, China
- Kaiwen Cheng
- Department of Ophthalmology, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Kaiwen Cheng
- Eye Institute, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Kaiwen Cheng
- NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Kaiwen Cheng
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Kaiwen Cheng
- State Key Laboratory of Medical Neurobiology, Shanghai, China
- Shuyu Liu
- Department of Ophthalmology, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Shuyu Liu
- Eye Institute, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Shuyu Liu
- NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Shuyu Liu
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Shuyu Liu
- State Key Laboratory of Medical Neurobiology, Shanghai, China
- Keke Zhang
- Department of Ophthalmology, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Keke Zhang
- Eye Institute, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Keke Zhang
- NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Keke Zhang
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Keke Zhang
- State Key Laboratory of Medical Neurobiology, Shanghai, China
- Yu Du
- Department of Ophthalmology, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Yu Du
- Eye Institute, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Yu Du
- NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Yu Du
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Yu Du
- State Key Laboratory of Medical Neurobiology, Shanghai, China
- Yi Lu
- Department of Ophthalmology, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Yi Lu
- Eye Institute, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Yi Lu
- NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Yi Lu
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Yi Lu
- State Key Laboratory of Medical Neurobiology, Shanghai, China
- Xiangjia Zhu
- Department of Ophthalmology, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Xiangjia Zhu
- Eye Institute, Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China
- Xiangjia Zhu
- NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Xiangjia Zhu
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Xiangjia Zhu
- State Key Laboratory of Medical Neurobiology, Shanghai, China
- DOI
- https://doi.org/10.3389/fmed.2023.1306276
- Journal volume & issue
-
Vol. 10
Abstract
PurposeThis study aims to explore the relationships between lens diameter (LD) measured with ultrasound biomicroscopy (UBM) and ocular biometric parameters.MethodsOcular biometric parameters including axial length (AL), white-to-white distance (WTW), anterior chamber depth (ACD), lens thickness (LT) and anterior segment length (ASL) were measured with IOL-Master 700, and the direct measurement of LD was conducted through UBM (ArcScan Insight 100). Relationships between LD and ocular biometric parameters were then investigated. Eyes with AL ≥ 28 mm were defined as eyes with extreme myopia, and eyes with AL < 28 mm were defined as eyes without extreme myopia.ResultsA total of 194 eyes from 194 subjects were included. The mean LD was 9.58 ± 0.49 mm, ranging from 8.60 to 10.96 mm. According to univariate analysis, larger LD was associated with elder age, male gender, larger WTW, ACD and ASL (all p < 0.05). Meanwhile, the LD was positively correlated with AL in eyes without extreme myopia (p < 0.05), but not in eyes with extreme myopia (p > 0.05). Backward stepwise regressions revealed that a larger LD was associated with larger WTW, ASL and AL in eyes without extreme myopia (all p < 0.05), while ASL was the only significant variable in eyes with extreme myopia (p < 0.05).ConclusionLarger WTW, ASL and AL in eyes without extreme myopia, as well as longer ASL in eyes with extreme myopia indicated a larger LD, which provides guidance in personalized surgical choice and promises ideal visual outcomes.
Keywords
