Pifu-xingbing zhenliaoxue zazhi (Jun 2020)

Efficacy of narrow band intense pulsed light combined with long pulse 1 064 nm Nd∶YAG laser for infant port wine stain

  • Juan-juan YI,
  • Yan-tao CAI,
  • Li-qing CEN,
  • Jing YANG,
  • Jing ZHANG,
  • Pu-hui XIE,
  • Hui-zhen HUANG,
  • Yan TANG

DOI
https://doi.org/10.3969/j.issn.1674-8468.2020.03.004
Journal volume & issue
Vol. 27, no. 3
pp. 156 – 159

Abstract

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Objective: To investigate the efficacy and safety of narrow band intense pulsed light (DPL) combined with long pulse 1 064 nm Nd∶YAG laser for infant port wine stain. Methods: A total of 98 patients with infant port wine stain were randomly divided into two groups. The treatment group (58 cases) was treated with DPL and long pulse 1 064 nm Nd∶YAG laser for 3~5 treatment session at 4-week interval, while 40 patients treated with DPL alone served as controls. Follow-up was performed 1 month after the last treatment. Results: Combination of DPL and long pulse 1 064 nm Nd∶YAG laser displayed a total effective rate of 70.69%, including complete clearance (13 cases, 22.41%), marked improvement (16 cases, 27.58%), and some improvement (12 cases, 20.68%). In contrast, only 37.50% of patients treated with DPL alone showed improvement, including 2 cases of complete clearance (5.00%), 8 cases of marked improvement (20.00%), and 5 cases of some improvement (12.50%). Total effective rates differed significantly between the two groups (χ2=10.65, P<0.05). Blisters and scabs were observed in 5 cases (8.62%) in the treatment group, and 3 cases (7.50%) in patients treated with DPL alone (χ2=0.04, P=0.842). Conclusion: DPL combined with long pulse 1 064 nm Nd∶YAG laser is effective and safe for infant port wine stains.

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