mBio (Jun 2021)
Albumin Neutralizes Hydrophobic Toxins and Modulates <i>Candida albicans</i> Pathogenicity
- Sophie Austermeier,
- Marina Pekmezović,
- Pauline Porschitz,
- Sejeong Lee,
- Nessim Kichik,
- David L. Moyes,
- Jemima Ho,
- Natalia K. Kotowicz,
- Julian R. Naglik,
- Bernhard Hube,
- Mark S. Gresnigt
Affiliations
- Sophie Austermeier
- ORCiD
- Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany<?A3B2 show [zaq no="AQGRid1"]?>
- Marina Pekmezović
- ORCiD
- Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany<?A3B2 show [zaq no="AQGRid1"]?>
- Pauline Porschitz
- Junior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany
- Sejeong Lee
- ORCiD
- Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College London, London, United Kingdom
- Nessim Kichik
- Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College London, London, United Kingdom
- David L. Moyes
- ORCiD
- Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College London, London, United Kingdom
- Jemima Ho
- ORCiD
- Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College London, London, United Kingdom
- Natalia K. Kotowicz
- ORCiD
- Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College London, London, United Kingdom
- Julian R. Naglik
- ORCiD
- Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College London, London, United Kingdom
- Bernhard Hube
- ORCiD
- Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany<?A3B2 show [zaq no="AQGRid1"]?>
- Mark S. Gresnigt
- ORCiD
- Junior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany
- DOI
- https://doi.org/10.1128/mBio.00531-21
- Journal volume & issue
-
Vol. 12,
no. 3
Abstract
Albumin is the most abundant serum protein in humans. During inflammation, serum albumin levels decrease drastically, and low albumin levels are associated with poor patient outcome.