Antibacterial power of Olea Europaea extracts from different Moroccan regions

Abstract

The discovery of antibiotics has always been a medical advance that has improved the prognosis of infections. However, resistance to these products has evolved into a major health problem. Some diseases are even resistant to all antibiotics currently available on the market. A reduction in the use of antibiotics must be based on other approaches, namely the use of alternative treatments to antibiotics, such as phytotherapy. In the same objective our study focused on the research of the antibacterial power of Olea Europaea known for its various medicinal properties. 31 bacterial strains were tested for their susceptibility using the agar diffusion method, and we determined their MIC by the micro titration technique on microplates. Five bacteria belonged to the American collection (ATCC) and 26 strains isolated from nosocomial infections between the period of 2011 and 2015. We noticed that our aqueous, methanolic, ethanolic and ethyl acetate extracts are active against all tested bacteria. On the other hand, we observed that the hexane and dichloromethane extracts showed no inhibition effect on all the bacteria tested. The methanolic extract showed a higher MIC against ESBL enterobacteria (E. coli, E. cloacae, P. mirabilis) and imipenem-resistant A. baumanii. The lowest MIC was 1.56 ug / ml.

Keywords

• antibiotic resistance
• antibacterial activity
• olea europaea
• medicinal plants