Valores de referência da pressão inspiratória nasal em indivíduos saudáveis no Brasil: estudo multicêntrico Reference values for sniff nasal inspiratory pressure in healthy subjects in Brazil: a multicenter study

Abstract

OBJETIVO: Os objetivos do presente estudo foram determinar equações de referência para pressão inspiratória nasal (PIN) e propor equações de referência para a população brasileira. MÉTODOS: Foram avaliados 243 indivíduos saudáveis (111 homens e 132 mulheres), entre 20 e 80 anos, com CVF > 80% e razão VEF1/CVF > 85% do predito. Todos os indivíduos realizaram testes de força muscular respiratória para a determinação de PIN, PImáx e PEmáx. RESULTADOS: Os valores da PIN foram maiores no sexo masculino que no feminino (p OBJECTIVE: The objectives of this study were to determine reference values for sniff nasal inspiratory pressure (SNIP) and to propose reference equations for the population of Brazil. METHODS: We evaluated 243 healthy individuals (111 males and 132 females), between 20 and 80 years of age, with an FVC and FEV1/FVC ratio > 80% and > 85% of the predicted value, respectively. All of the subjects underwent respiratory muscle strength tests to determine MIP, MEP, and SNIP. RESULTS: We found that SNIP values were higher in males than in females (p < 0.05) and that SNIP correlated negatively with age, for males (r = -0.29; p < 0.001) and for females (r = -0.33; p < 0.0001). Linear regression also revealed that age influenced the predicted SNIP, for males (R² = 0.09) and females (R² = 0.10). We obtained predicted SNIP values that were higher than those obtained for other populations. CONCLUSIONS: We have devised predictive equations for SNIP to be used in adults (20-80 years of age) in Brazil. These equations could help minimize diagnostic discrepancies among individuals.

Keywords

• Músculos Respiratórios
• Testes de Função Respiratória
• Valores de Referência
• Modelos Lineares
• Respiratory Muscles
• Respiratory Function Tests
• Reference Values
• Linear Models