Synthesis and characterization of Molybdenum(VI) complex with 4-methoxy Salicylaldehyde 2-aminobenzoylhydrazon and investigation of their antibacterial activity

Abstract

In the study, reaction of the 4-methoxy salicylaldehyde 2-aminobenzoylhydrazone(H2L) with MoO2(acac)2 formed a 5-coordinate Molybdenum(VI) complex [MoO2L]. The synthesized complex and its ligand were characterized with various techniques such as NMR, UV-Vis, FT-IR Spectroscopy and elemental analysis (CHN). Molecular structure of Mo(VI) complex is determined by X-ray crystallography , indicating the dianionic tridentate. The crystallographic data revealed a distorted square-pyramidal geometry.The biological activities of Schiff base ligand, H2L, and the biological role of Mo(VI) metal ion in vitro conditions against four strains of bacterial standard Gram positive and Gram negative investigated. The results indicated that the highest antibacterial activity against Escherichia coli was related to the MoO2L complex. The results of the present study showed that the complex had a stronger antibacterial activity than ligand.

Keywords

• schiff base
• antibacterial activity
• molybdnum(vi) complex
• acylhydrazone