When muscle quivers and undulates

Abstract

Abstract We describe a patient who presented with fatigue and pulling sensation in his lower limbs. He had continuous muscle contractions over his trunk (myokymia) which pointed towards the diagnosis of Isaacs syndrome which was confirmed by strongly positive CASPR2 antibodies in blood.

Keywords

• acquired neuromyotonia
• CASPR2 antibodies
• Isaacs syndrome
• Myokymia