InDel and CNV within the <i>AKAP13</i> Gene Revealing Strong Associations with Growth Traits in Goat

Abstract

A-kinase-anchoring protein 13 (AKAP13) is a member of the AKAP protein family that has been found to be associated with bone formation. Thus, we investigated the AKAP13 gene as a potential candidate gene for molecular-marker-assisted selection (MAS) in breeding. Our aim was to explore genetic variations (InDel and CNV) within the AKAP13 gene of Shaanbei white cashmere (SBWC) goats and analyze their relationship with growth traits. Ultimately, we identified three InDel loci (16-bp deletion, 15-bp insertion, and 25-bp deletion) and three CNVs, and the 16-bp and 15-bp loci were significantly associated with goat body length (p p p AKAP13 gene.

Keywords

• goat
• <i>AKAP13</i>
• InDel
• CNV (copy number variation)
• growth trait