Are platelet volume indices related to mortality in hospitalized children on mechanical ventilation?

Abstract

Objectives To investigate platelet volume indices and in-hospital mortality in children on mechanical ventilation. Methods This retrospective study included children aged 3 years, procalcitonin (OR 1.01, 95% CI 1.0, 1.01) and lactic acid (OR 1.22, 95% CI 1.09, 1.35) were associated with mortality. Platelet volume indices on admission were not independently associated with mortality in either group. Mean platelet volume (MPV) and platelet distribution width (PDW) showed different trends in non-survivors versus survivors over 1 week in both age groups. Conclusions Platelet volume indices may be associated with mortality in critically ill children receiving mechanical ventilation.