Comparative Evaluation of Formocresol, Propolis and Growth Factor as Pulpotomy Medicaments in Deciduous Teeth- An Invivo Study

Abstract

Introduction: Formocresol (FC) has evolved as the preferred medicament for routine pulpotomy procedures in pedodontics. With the introduction of newer materials, the emphasis has shifted towards regeneration. In this scenario, novel materials such as Platelet derived growth factor (PDGF) and Propolis (PS) have been considered. Aim: To compare and evaluate FC, PS and PDGF as pulpotomy agents clinically, radiographically and histologically in primary teeth. Materials and Methods: Ninety human primary teeth from children aged between 5-10 years were divided into three equal groups in whom pulpotomy procedure was performed and they were recalled after three and six months interval for clinical, radiographical and histological evaluation. Observations were subjected to statistical analysis using pearson chi-square test. Results: The results obtained indicated greater clinical and radiographical success for PDGF group (96.3%, 88.89%) followed by PS group (96.3%, 88.4%) and FC group (76%, 72%). Histological examination showed thick and continuous dentin bridge formation with minimal inflammation in both PS and PDGF group. Conclusion: PDGF and PS showed greater efficacy than FC clinically, radiographically and histologically with PDGF relatively having a lead in success rate. Thus, justifying their use as a novel and promising pulpotomy medicaments with regenerative property.

Keywords

• novel pulpotomy materials
• platelet derived growth factor
• regenerative approach
• vital pulp therapy