Nature Communications (Mar 2020)

Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans

  • D. A. Martins,
  • N. Mazibuko,
  • F. Zelaya,
  • S. Vasilakopoulou,
  • J. Loveridge,
  • A. Oates,
  • S. Maltezos,
  • M. Mehta,
  • S. Wastling,
  • M. Howard,
  • G. McAlonan,
  • D. Murphy,
  • S. C. R. Williams,
  • A. Fotopoulou,
  • U. Schuschnig,
  • Y. Paloyelis

DOI
https://doi.org/10.1038/s41467-020-14845-5
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 16

Abstract

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Intranasal oxytocin can affect brain function either by direct entry to the brain or by increasing oxytocin levels in blood plasma. Here, the authors show that increases in plasmatic oxytocin account for some but not all of the changes observed following intranasal oxytocin administration.