mBio (Oct 2019)

A Bumpy Pathway to Stationary-Phase Survival in <named-content content-type="genus-species">Bacillus subtilis</named-content>

  • Wayne L. Nicholson

DOI
https://doi.org/10.1128/mBio.02461-19
Journal volume & issue
Vol. 10, no. 5

Abstract

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ABSTRACT Bacillus subtilis cells can mount a number of responses to nutritional deprivation but ultimately either form dormant spores or enter a metabolically quiescent state. In a recent article (mBio 10:e01414-19, https://doi.org/10.1128/mBio.01414-19, 2019), R. Hashuel and S. Ben-Yehuda report on a novel means by which nutrient-starved B. subtilis cells escape from aging (days-old) colonies by accumulating mutations enabling them to continue growth under nutrient-limited conditions. They postulate that such a strategy may be a major factor determining the dynamics of bacterial populations in natural environments.

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