Resection of a Recurrent Metastatic Leptomeningeal Melanoma: Case Report and Literature Review

Abstract

Malignant melanoma is considered the most aggressive among all cutaneous cancer. Malignant melanoma commonly causes cerebral metastasis. The survival rate of melanoma with cerebral metastases is considerably poor. Surgical resection, radiotherapy, and chemotherapy are often used to increase overall survival. In this case report we present a fifty-four-year-old female with recurrent leptomeningeal metastatic malignant melanoma after gross total resection, with an additional literature review of the management. We describe how gross tumor resection results in an immediate clinical improvement in symptomatology in this patient who has previously undergone tumor resection.

Keywords

• Malignant melanoma
• Decompressive craniectomy
• Brain neoplasm
• Neoplasm recurrence