Positioning of centrioles is a conserved readout of Frizzled planar cell polarity signalling

Jose Maria Carvajal-Gonzalez; Angel-Carlos Roman; Marek Mlodzik

doi:10.1038/ncomms11135

Nature Communications (Mar 2016)

Positioning of centrioles is a conserved readout of Frizzled planar cell polarity signalling

Jose Maria Carvajal-Gonzalez,
Angel-Carlos Roman,
Marek Mlodzik

Affiliations

Jose Maria Carvajal-Gonzalez: Department of Developmental & Regenerative Biology, Tisch Cancer Institute, and Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai
Angel-Carlos Roman: Champalimaud Neuroscience Programme
Marek Mlodzik: Department of Developmental & Regenerative Biology, Tisch Cancer Institute, and Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai

DOI: https://doi.org/10.1038/ncomms11135
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 9

Abstract

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Planar cell polarity (PCP) contributes to cellular orientation during development but how this is regulated in Drosophilais unclear. Here, the authors identify Frizzled-PCP signalling as regulating polarised centriole positioning in the wing disc.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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