Journal of Contemporary Brachytherapy (Oct 2020)

Salvage high-dose-rate interstitial brachytherapy for perineal recurrence of prostate cancer after surgery and radiotherapy: a case report

  • Andrea Vavassori,
  • Stefano Durante,
  • Matteo Augugliaro,
  • Stefania Comi,
  • Raffaella Cambria,
  • Federica Cattani,
  • Roberta Lazzari,
  • Deliu Victor Matei,
  • Ottavio De Cobelli,
  • Roberto Orecchia,
  • Barbara Jereczek-Fossa

DOI
https://doi.org/10.5114/jcb.2020.100383
Journal volume & issue
Vol. 12, no. 5
pp. 492 – 496

Abstract

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Perineal seeding of tumor cells from prostate cancer (PCa) is very rare, and no standard treatment exists for this atypical presentation with no evidence of distant metastases. Local excision or external beam radiotherapy are used as local salvage treatments for such perineal masses, including those occurring after biopsy, surgery, or interstitial brachytherapy. We report on a patient who presented no evidence of disease and no late urinary or gastrointestinal toxicities at 58 months after receiving high-dose-rate brachytherapy (HDR-BT) for perineal recurrence of PCa after radical prostatectomy and salvage external beam radiotherapy. To the best of our knowledge, this is the first case treated with HDR-BT in this scenario.

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