Marine Drugs (Oct 2010)
Excavatoids O and P, New 12-Hydroxybriaranes from the Octocoral Briareum excavatum
Abstract
Two new 12-hydroxybriarane diterpenoids, designated as excavatoids O (1) and P (2), were isolated from the octocoral Briareum excavatum. The structures of briaranes 1 and 2 were established on the basis of extensive spectral data analysis. Excavatoid P (2) is the first metabolite which possesses a 6b-chlorine atom in briarane analogues.
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