Conserved and species-specific chromatin remodeling and regulatory dynamics during mouse and chicken limb bud development

Shalu Jhanwar; Jonas Malkmus; Jens Stolte; Olga Romashkina; Aimée Zuniga; Rolf Zeller

doi:10.1038/s41467-021-25935-3

Nature Communications (Sep 2021)

Conserved and species-specific chromatin remodeling and regulatory dynamics during mouse and chicken limb bud development

Shalu Jhanwar,
Jonas Malkmus,
Jens Stolte,
Olga Romashkina,
Aimée Zuniga,
Rolf Zeller

Affiliations

Shalu Jhanwar: Developmental Genetics, Department of Biomedicine, University of Basel
Jonas Malkmus: Developmental Genetics, Department of Biomedicine, University of Basel
Jens Stolte: Developmental Genetics, Department of Biomedicine, University of Basel
Olga Romashkina: Developmental Genetics, Department of Biomedicine, University of Basel
Aimée Zuniga: Developmental Genetics, Department of Biomedicine, University of Basel
Rolf Zeller: Developmental Genetics, Department of Biomedicine, University of Basel

DOI: https://doi.org/10.1038/s41467-021-25935-3
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 17

Abstract

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The vertebrate limb bud is a paradigm to uncover the fundamental mechanisms that govern embryogenesis and evolutionary diversification. Here the authors compare mouse and chicken limb bud development to study the impact of genome evolution on conserved and divergent gene regulatory interactions.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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