Peutz-Jeghers Syndrome without Polyposis

Abstract

Peutz-Jeghers syndrome is generally considered a condition in which familial gastrointestinal polyposis is associated with a characteristic pigmentation of the skin and mucous membranes Two members of a family in which the characteristic pigmentation was present in the absence of gastrointestinal polyposis arc reported. These patients highlight the importance of defining the intestinal lesion associated with this syndrome.