[1–9-NαC]-Linusorb B3 (Cyclolinopeptide A) dimethyl sulfoxide monosolvate

Abstract

Crystals of the dimethyl sulfoxide (DMSO) solvate of [1–9-NαC]-linusorb B3 (Cyclolinopeptide A; CLP-A; C57H84N9O9·C2H6OS), a cyclic polypeptide were obtained following peptide extraction and purification from flaxseed oil. There are four intramolecular N—H...O hydrogen bonds. In the crystal, the molecules are linked in chains along the a axis by N—H...O hydrogen bonds. Each DMSO O atom accepts a hydrogen bond from an NH group at the Phe6 location in the CLP-A molecule.

Keywords

• crystal structure
• cyclic peptide
• orbitides
• cyclolinopeptide a
• [1–9-nαc]-linusorb b3
• dimethyl sulfoxide
• hydrogen bonding