A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

Abstract

Transcription regulation requires recruitment of different epigenetic regulators to the chromatin. Here the authors provide evidence that an H3K36me3 reader PWWP2A forms a variant NuRD complex and plays a role in regulating transcription and histone acetylation dynamics.