PLoS ONE (Jan 2013)

Factors associated with adenoma detection rate and diagnosis of polyps and colorectal cancer during colonoscopy in France: results of a prospective, nationwide survey.

  • Maximilien Barret,
  • Christian Boustiere,
  • Jean-Marc Canard,
  • Jean-Pierre Arpurt,
  • David Bernardini,
  • Philippe Bulois,
  • Stanislas Chaussade,
  • Denis Heresbach,
  • Isabelle Joly,
  • Jean Lapuelle,
  • René Laugier,
  • Gilles Lesur,
  • Patrice Pienkowski,
  • Thierry Ponchon,
  • Bertrand Pujol,
  • Bruno Richard-Molard,
  • Michel Robaszkiewicz,
  • Rémi Systchenko,
  • Fatima Abbas,
  • Anne-Marie Schott-Pethelaz,
  • Christophe Cellier,
  • Société Française d'Endoscopie Digestive

DOI
https://doi.org/10.1371/journal.pone.0068947
Journal volume & issue
Vol. 8, no. 7
p. e68947

Abstract

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IntroductionColonoscopy can prevent deaths due to colorectal cancer (CRC) through early diagnosis or resection of colonic adenomas. We conducted a prospective, nationwide study on colonoscopy practice in France.MethodsAn online questionnaire was administered to 2,600 French gastroenterologists. Data from all consecutive colonoscopies performed during one week were collected. A statistical extrapolation of the results to a whole year was performed, and factors potentially associated with the adenoma detection rate (ADR) or the diagnosis of polyps or cancer were assessed.ResultsA total of 342 gastroenterologists, representative of the overall population of French gastroenterologists, provided data on 3,266 colonoscopies, corresponding to 1,200,529 (95% CI: 1,125,936-1,275,122) procedures for the year 2011. The indication for colonoscopy was CRC screening and digestive symptoms in 49.6% and 38.9% of cases, respectively. Polypectomy was performed in 35.5% of cases. The ADR and prevalence of CRC were 17.7% and 2.9%, respectively. The main factors associated with a high ADR were male gender (p=0.0001), age over 50 (p=0.0001), personal or family history of CRC or colorectal polyps (pConclusionsFor the first time in France, we report nationwide prospective data on colonoscopy practice, including histological results. We found an average ADR of 17.7%, and observed reduced CRC incidence in patients with previous colonoscopy.