Bioingeniøren (Dec 2010)
Thromboelastography in clinical use
Abstract
Background: Thromboelastography provides a functional evaluation of the coagulation process. By measuring viscoelastic changes during the haemostatic process thromboelastography provides a real-time evaluation of the coagulation cascade and the interaction of the different elements that participate in the coagulation process. Thus, thromboelastography has the potential for individualising transfusion therapy. Material and methods: This review article is based on selected publications, search in PubMed and the authors’ own experience. Results: Thromboelastography has an established role in cardiopulmonary bypass and liver surgery. There is also expanding evidence for the usefulness of thromboelastography in the management of trauma-induced coagulopathy and obstetric medicine. Transfusion guidelines based on thromboelastography can reduce the use of allogeneic blood, thus minimising inappropriate blood product use. Interpretation: Thromboelastography can be a useful tool for individualising transfusion therapy. In order to utilise the potential of thromboelastography the physician treating the patient needs to receive results swiftly, preferentially in real-time.
