Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo

Laura Macca; Lucia Peterle; Manuela Ceccarelli; Ylenia Ingrasciotta; Giuseppe Nunnari; Claudio Guarneri

doi:10.3390/vaccines10101647

Vaccines (Sep 2022)

Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo

Laura Macca,
Lucia Peterle,
Manuela Ceccarelli,
Ylenia Ingrasciotta,
Giuseppe Nunnari,
Claudio Guarneri

Affiliations

Laura Macca: Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, Italy
Lucia Peterle: Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, Italy
Manuela Ceccarelli: Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, University of Catania, Catania, Italy C/O ARNAS “Garibaldi”, “Nesima” Hospital, Via Palermo 636, 95122 Catania, Italy
Ylenia Ingrasciotta: Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Pharmacology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, Italy
Giuseppe Nunnari: Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, Italy
Claudio Guarneri: Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Dermatology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, Italy

DOI: https://doi.org/10.3390/vaccines10101647
Journal volume & issue: Vol. 10, no. 10
p. 1647

Abstract

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Several cutaneous manifestations in patients undergoing COVID-19 vaccination have been described in the literature. Herein, we presented a case of new-onset vitiligo that occurred after the second dose of the Comirnaty vaccine. An updated literature search revealed the occurrence of a total of 16 cases, including new-onset or worsening of preexisting vitiligo. Given the autoimmune pathogenesis of the disease, we reviewed and discussed the potential role of the vaccine prophylaxis as a trigger for the development of such hypopigmented skin lesions.

Published in Vaccines

ISSN: 2076-393X (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine
Website: http://www.mdpi.com/journal/vaccines

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Abstract

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