Thoracic Cancer (Sep 2021)

Pseudocirrhosis due to liver metastasis from lung adenocarcinoma

  • Naoki Shijubou,
  • Toshiyuki Sumi,
  • Yoshiko Keira,
  • Hideaki Shiraishi,
  • Yuta Nagahisa,
  • Keigo Matsuura,
  • Motoki Sekikawa,
  • Yuichi Yamada,
  • Hisashi Nakata,
  • Hirofumi Chiba

DOI
https://doi.org/10.1111/1759-7714.14084
Journal volume & issue
Vol. 12, no. 17
pp. 2407 – 2410

Abstract

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Abstract Pseudocirrhosis is a radiological diagnosis of cirrhosis without histological evidence and occurs as a complication of liver metastases from solid tumors. A 50‐year‐old man without any previous history of liver disease was diagnosed with adenocarcinoma of the left upper lung lobe and liver metastasis. After chemotherapy, the liver metastases shrank; however, over time, the liver shrank and showed cirrhosis‐like morphological changes. His performance status deteriorated due to ascites and leg edema, and chemotherapy was terminated. Physicians treating lung adenocarcinoma with liver metastases should be aware that pseudocirrhosis is a rare but important complication that can worsen performance status (PS) and hinder treatment continuation.

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