A new non-invasive method for assessing steatosis in chronic liver diseases

Abstract

Aim. To assess the diagnostic accuracy of the controlled attenuation parameter (CAP) to determine the grade of hepatic steatosis (HS) in patients with chronic liver diseases (CLD) of different etiologies and to compare the obtained results with morphological findings. Subjects and methods. A total of 45 patients (18 men and 27 women) aged 25 to 73 years with CLD were examined. All the patients underwent liver puncture biopsy for assessing the HS index and fibrosis stage, as well as determination of hepatic elasticity (F, kPa) for estimating the stage of fibrosis and the grade of HS by CAP (S, dB/m) using a FibroScan device. When assessing HS, the CAP values of

Keywords

• hepatic steatosis
• steatohepatitis
• fibrosis
• cirrhosis
• liver puncture biopsy
• non-invasive tests
• steatosis index
• transient elastography
• controlled attenuation parameter (cap)
• area under the receiver operating characteristics curve (auroc)
• auroc