Investigation of hemodynamic markers for stenosis development

Abstract

Abstract Different hemodynamic markers for stenosis development are considered, assessed and compared. A recently proposed numerical approach is employed, where stenosis development is modeled based on the local hemodynamic conditions at the artery wall, determined using the lattice Boltzmann method. A range of hemodynamic markers, commonly associated in the literature with the progression of atherosclerosis, were considered. It was observed that using the oscillatory shear index, which is related to the wall shear stress oscillating from its mean direction, did not produce a realistic stenosis development. The other markers produced stenosis growth comparable with observations from the literature.

Keywords

• blood flow modeling
• carotid artery
• hemodynamic markers for atherosclerosis
• lattice Boltzmann method