Does The Mean Platelet Volume (MPV) Have Any Importance In the Evaluation of Cardiovascular Disease In COPD Patients?

Abstract

INTRODUCTION: Mean platelet volume (MPV) is an index of platelet activation. In this study, we aimed to evaluate the relationship between in patients with COPD and cardiovasculary disease who present to chest diseases department and MPV. METHODS: : Smoker 535 (71.80%) and non-smoker, 210 (28.20%) subjects were compared for MPV and other parameters. Accordingly, patients with and without COPD were compared in terms of MPV and other parameters. RESULTS: The levels of white blood cells (Wbc), hemoglobin (Hgb) and hematocrit (Htc) in smokers were statistically significantly higher than non-smokers (p<0.001). The level of MPV in smokers was statistically higher than non-smokers [the levels of MPV were, 10.10 (8-14.20), 9.60 (6.40-11.80),respectively p<0.001]. There were 106 cases of COPD among smokers. The differences in levels of platelets and MPV between patients with COPD and nonsmoker patients without COPD were [10.20 (8.30-14), 9.60 (6.40-11.80), respectively p=0.001] statistically significant. Also, MPV levels of COPD patients with cardiovascular comorbidities (CVC) were higher than that of the patients without CVC. DISCUSSION AND CONCLUSION: In this study, higher MPV and higher platelet values have been shown in smokers and COPD patients compared with non- smokers. As a result, consider that high MPV levels may increase the tendency to thrombosis, with COPD. However, further larger studies are warranted about the relationship of COPD with MPV and CVC.

Keywords

• cigarette
• copd
• mpv
• thrombosis.