Emerging Infectious Diseases (Nov 2024)

Prevalence of Pertactin-Deficient Bordetella pertussis Isolates, Slovenia

  • Alex-Mikael Barkoff,
  • Tamara Kastrin,
  • Katja Seme,
  • Marta Grgič Vitek,
  • Jussi Mertsola,
  • Qiushui He

DOI
https://doi.org/10.3201/eid3011.231393
Journal volume & issue
Vol. 30, no. 11
pp. 2429 – 2432

Abstract

Read online

In Slovenia, primary acellular pertussis vaccines (ACVs) containing pertactin (PRN) were mostly used during 1999–2016; ACVs without PRN were introduced in 2017. Among 123 Bordetella pertussis strains collected during 2002–2020, a total of 48 were PRN-deficient; 44 were collected after 2017. Changes to ACVs could increase PRN-deficient B. pertussis and infections.

Keywords