The administration of the synthetic peptide YMESRADR with a low aspirin dose significantly augments its antiplatelet effect, in contrast to the highly constrained peptide (S,S) PSRCDCR-NH2. An experimental study

• K.V. Englezopoulos,
• E.M. Stathopoulou,
• V. Moussis,
• V.G. Chantzichristos,
• N.D. Papamichael,
• P.T. Tatsidou,
• V.D. Roussa,
• M.E. Tsoumani,
• L. Lakkas,
• A. Rammos,
• C.S. Katsouras,
• E. Fotou,
• V. Tsikaris,
• A.D. Tselepis,
• L.K. Michalis

Affiliations

K.V. Englezopoulos

Corresponding author. Englezopoulos KV, B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece. Tel.: +306974303606.; B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece

E.M. Stathopoulou

Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece

V. Moussis

Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece

V.G. Chantzichristos

Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece

N.D. Papamichael

B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece

P.T. Tatsidou

Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece

V.D. Roussa

B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece

M.E. Tsoumani

Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece

L. Lakkas

B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece

A. Rammos

B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece

C.S. Katsouras

B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece

E. Fotou

Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece

V. Tsikaris

Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece

A.D. Tselepis

Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece

L.K. Michalis

B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece