Nature Communications (Jan 2020)

Virulent coliphages in 1-year-old children fecal samples are fewer, but more infectious than temperate coliphages

  • Aurélie Mathieu,
  • Moïra Dion,
  • Ling Deng,
  • Denise Tremblay,
  • Elisabeth Moncaut,
  • Shiraz A. Shah,
  • Jakob Stokholm,
  • Karen A. Krogfelt,
  • Susanne Schjørring,
  • Hans Bisgaard,
  • Dennis S. Nielsen,
  • Sylvain Moineau,
  • Marie-Agnès Petit

DOI
https://doi.org/10.1038/s41467-019-14042-z
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

Read online

The impact of bacteriophages in the human gut microbiome remains poorly understood. Here, the authors characterize coliphages isolated from a large cohort of 1-year-old infants and show that temperate coliphages dominate, while virulent ones have greater infectivity and broader host range.