Atmosphere (Jul 2019)
The Establishment of the Household Air Pollution Consortium (HAPCO)
- H. Dean Hosgood,
- Madelyn Klugman,
- Keitaro Matsuo,
- Alexandra J. White,
- Atsuko Sadakane,
- Xiao-Ou Shu,
- Ruy Lopez-Ridaura,
- Aesun Shin,
- Ichiro Tsuji,
- Reza Malekzadeh,
- Nolwenn Noisel,
- Parveen Bhatti,
- Gong Yang,
- Eiko Saito,
- Shafiur Rahman,
- Wei Hu,
- Bryan Bassig,
- George Downward,
- Roel Vermeulen,
- Xiaonan Xue,
- Thomas Rohan,
- Sarah K. Abe,
- Philippe Broët,
- Eric J. Grant,
- Trevor J. B. Dummer,
- Nat Rothman,
- Manami Inoue,
- Martin Lajous,
- Keun-Young Yoo,
- Hidemi Ito,
- Dale P. Sandler,
- Habib Ashan,
- Wei Zheng,
- Paolo Boffetta,
- Qing Lan
Affiliations
- H. Dean Hosgood
- Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
- Madelyn Klugman
- Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
- Keitaro Matsuo
- Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute; Nagoya 464-8681, Japan
- Alexandra J. White
- Epidemiology Branch, National Institute of Environmental Health Science, Research Triangle Park, NC 27709, USA
- Atsuko Sadakane
- Department of Epidemiology, Radiation Effects Research Foundation, Hiroshima 732-0815, Japan
- Xiao-Ou Shu
- Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Vanderbilt University Medicine Center, Nashville, TN 37203-1738, USA
- Ruy Lopez-Ridaura
- National Institute of Public Health, Cuernavaca, Morelos 62100, Mexico
- Aesun Shin
- Department of Preventative Medicine, Seoul National University College of Medicine, Seoul 03080, Korea
- Ichiro Tsuji
- Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University Graduate School of Medicine, Miyagi 980-8575, Japan
- Reza Malekzadeh
- Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran 14117, Iran
- Nolwenn Noisel
- CARTaGENE, Centre de Recherche du CHU Sainte-Justine, Montreal, QC H3T 1C5, Canada
- Parveen Bhatti
- BC Cancer, Vancouver, BC V5Z 1L3, Canada
- Gong Yang
- Center for Health Services, Vanderbilt University School of Medicine, Nashville, TN 37203-1738, USA
- Eiko Saito
- Division of Cancer Statistics and Integration, Center for Cancer Control and Information Services, National Cancer Center, Tokyo 104-0045, Japan
- Shafiur Rahman
- Department of Global Health Policy, Graduate School of Medicine, University of Tokyo, Tokyo 113-8654, Japan
- Wei Hu
- Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7240, USA
- Bryan Bassig
- Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7240, USA
- George Downward
- Institute for Risk Assessment Services, Utrecht University, 3508 Utrecht, The Netherlands
- Roel Vermeulen
- Institute for Risk Assessment Services, Utrecht University, 3508 Utrecht, The Netherlands
- Xiaonan Xue
- Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
- Thomas Rohan
- Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
- Sarah K. Abe
- Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo 104-0045, Japan
- Philippe Broët
- CARTaGENE, Centre de Recherche du CHU Sainte-Justine, Montreal, QC H3T 1C5, Canada
- Eric J. Grant
- Department of Epidemiology, Radiation Effects Research Foundation, Hiroshima 732-0815, Japan
- Trevor J. B. Dummer
- School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada
- Nat Rothman
- Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7240, USA
- Manami Inoue
- Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo 104-0045, Japan
- Martin Lajous
- National Institute of Public Health, Cuernavaca, Morelos 62100, Mexico
- Keun-Young Yoo
- Department of Preventative Medicine, Seoul National University College of Medicine, Seoul 03080, Korea
- Hidemi Ito
- Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute; Nagoya 464-8681, Japan
- Dale P. Sandler
- Epidemiology Branch, National Institute of Environmental Health Science, Research Triangle Park, NC 27709, USA
- Habib Ashan
- Department of Health Sciences, The University of Chicago, Chicago, IL 60637, USA
- Wei Zheng
- Center for Health Services, Vanderbilt University School of Medicine, Nashville, TN 37203-1738, USA
- Paolo Boffetta
- The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY 10029-6574, USA
- Qing Lan
- Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7240, USA
- DOI
- https://doi.org/10.3390/atmos10070422
- Journal volume & issue
-
Vol. 10,
no. 7
p. 422
Abstract
Household air pollution (HAP) is of public health concern, with ~3 billion people worldwide (including >15 million in the US) exposed. HAP from coal use is a human lung carcinogen, yet the epidemiological evidence on carcinogenicity of HAP from biomass use, primarily wood, is not conclusive. To robustly assess biomass’s carcinogenic potential, prospective studies of individuals experiencing a variety of HAP exposures are needed. We have built a global consortium of 13 prospective cohorts (HAPCO: Household Air Pollution Consortium) that have site- and disease-specific mortality and solid fuel use data, for a combined sample size of 587,257 participants and 57,483 deaths. HAPCO provides a novel opportunity to assess the association of HAP with lung cancer death while controlling for important confounders such as tobacco and outdoor air pollution exposures. HAPCO is also uniquely positioned to determine the risks associated with cancers other than lung as well as nonmalignant respiratory and cardiometabolic outcomes, for which prospective epidemiologic research is limited. HAPCO will facilitate research to address public health concerns associated with HAP-attributed exposures by enabling investigators to evaluate sex-specific and smoking status-specific effects under various exposure scenarios.
Keywords
