Population genomics and antimicrobial resistance dynamics of Escherichia coli in wastewater and river environments

Jose F. Delgado-Blas; Cristina M. Ovejero; Sophia David; Natalia Montero; William Calero-Caceres; M. Pilar Garcillan-Barcia; Fernando de la Cruz; Maite Muniesa; David M. Aanensen; Bruno Gonzalez-Zorn

doi:10.1038/s42003-021-01949-x

Communications Biology (Apr 2021)

Population genomics and antimicrobial resistance dynamics of Escherichia coli in wastewater and river environments

Jose F. Delgado-Blas,
Cristina M. Ovejero,
Sophia David,
Natalia Montero,
William Calero-Caceres,
M. Pilar Garcillan-Barcia,
Fernando de la Cruz,
Maite Muniesa,
David M. Aanensen,
Bruno Gonzalez-Zorn

Affiliations

Jose F. Delgado-Blas: Antimicrobial Resistance Unit (ARU), Animal Health Department, Faculty of Veterinary Medicine and VISAVET Health Surveillance Centre, Complutense University of Madrid
Cristina M. Ovejero: Antimicrobial Resistance Unit (ARU), Animal Health Department, Faculty of Veterinary Medicine and VISAVET Health Surveillance Centre, Complutense University of Madrid
Sophia David: Centre for Genomic Pathogen Surveillance (CGPS), Wellcome Sanger Institute
Natalia Montero: Antimicrobial Resistance Unit (ARU), Animal Health Department, Faculty of Veterinary Medicine and VISAVET Health Surveillance Centre, Complutense University of Madrid
William Calero-Caceres: Department of Genetics, Microbiology and Statistics, Faculty of Biology, University of Barcelona
M. Pilar Garcillan-Barcia: Institute of Biomedicine and Biotechnology (IBBTEC), CSIC, University of Cantabria
Fernando de la Cruz: Institute of Biomedicine and Biotechnology (IBBTEC), CSIC, University of Cantabria
Maite Muniesa: Department of Genetics, Microbiology and Statistics, Faculty of Biology, University of Barcelona
David M. Aanensen: Centre for Genomic Pathogen Surveillance (CGPS), Wellcome Sanger Institute
Bruno Gonzalez-Zorn: Antimicrobial Resistance Unit (ARU), Animal Health Department, Faculty of Veterinary Medicine and VISAVET Health Surveillance Centre, Complutense University of Madrid

DOI: https://doi.org/10.1038/s42003-021-01949-x
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 13

Abstract

Read online

Jose F. Delgado-Blas et al. report a genomic analysis of two antimicrobial-resistant E. coli populations from wastewater and river water. They find that bacteria from wastewater are more resistant to antibiotics and rely on a diverse set of plasmids for adaptation, while river bacteria adapt mainly via chromosomal changes.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal