Zhongguo linchuang yanjiu (Jul 2024)
Application value of real-time continuous glucose monitoring in orthopedic patients with type 2 diabetes mellitus during perioperative period
Abstract
"Objective To explore the application and effect of real-time continuous glucose monitoring (RT-CGM) in orthopedic perioperative patients with type 2 diabetes mellitus (T2DM). Methods As a single-center, prospective, randomized controlled trail, 40 orthopedic patients with T2DM during perioperative period in the Department of Othopedics of Nanjing Drum Tower Hospital from January to May 2023 were selected and assigned to the experimental group(RT-CGM with insulin subcutaneous pump group,n=20) and the control group(insulin subcutaneous pump group,n=20) by minimum random grouping method in dynamic randomization method. The differences in time in range (TIR),time above range (TAR), time below range (TBR), mean blood glucose (MBG), preoperative waiting time, and postoperative hospital stay were compared between the two groups. Results The TIR of the experimental group was significantly higher than that of the control group ［（62.56±13.55）%vs（44.60±15.14）%,t=3.953,P＜0.01）, and the TAR was significantly lower than that of the control group［（37.26±13.44 ）%vs（55.21±15.20）%,t=3.957,P＜0.01］, and there was no significant difference in the TBR between the two groups (P＞0.05). The MBG level in the experimental group was significantly lower than that in the control group［（9.81±1.54）mmol/Lvs (12.06±1.96) mmol/L,t=4.036,P＜0.01］. The preoperative waiting time of the experimental group were lower than that of the control group ［(3.25±1.74) dvs (4.60±1.96) d,t=2.303,P=0.027］, and the postoperative hospital stay was lower than that of the control group ［（4.90±2.36）dvs (6.65±2.80) d,t=2.139,P=0.039］. Conclusion RT-CGM can better control the blood glucose level of patients, reduce the hospitalization time, which has a higher clinical application value for orthopedic perioperative patients with T2DM."
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