P-80 SEVERELY OBESE PATIENTS HAD HEPATIC FIBROSIS EVEN WITHOUT METABOLIC SYNDROME

Abstract

Introduction: Metabolic Associated Fatty Liver Disease (MAFLD) is a clinic-pathological condition commonly associated with metabolic syndrome (MS) and this association is frequently found in severely obese. Objective: To compare clinical and histological characteristics of MAFLD in obese with and without MS. Methodology: Cross-sectional study with severely obese patients diagnosed with MAFLD between Sep/2014 and May/2015. MAFLD was diagnosed by liver biopsy during bariatric surgery. MS diagnosis was based on the International Diabetes Federation criteria. Statistical analyses were performed using chi-square and t tests. P<0.05 were considered significant. Results: Table 1 shows clinical and histological characteristics of the patients according to the presence of MS. Conclusion: The results reinforce the relevance of evaluating NAFLD in severely obese by histology. In this simple of obese with MAFLD had hepatic fibrosis, even those without MS.