Vibrio ruber (S2A1), a Marine Bacterium that Exhibits Significant Antimicrobial Activity

Abstract

A potential antimicrobial-producing marine bacterium, designated as S2A1, was isolated from a seagrass collected in Setiu Lagoon, Terengganu. S2A1 was a Gram negative rod that was motile by means of a polar flagellum. Phenotypic and genotypic characterisation indicated that strain S2A1 represented a species in the genus Vibrio. The antimicrobial activities of S2A1 against a number of test microorganisms showed a broad antimicrobial spectrum property with inhibition towards 25 out of 29 test microorganisms. The antimicrobial compound(s) of S2A1 was more effective against Gram-positive bacteria with 100% inhibition, compared to yeast (88.8%) and Gram-negative bacteria (75.0%) tested. High activity scores were observed when using whole cells compared to cell free extract.

Keywords

• Antimicrobial activity
• Gram positive bacterium
• Vibrio ruber