BMC Infectious Diseases (Oct 2020)

Orbital mucormycosis in immunocompetent children; review of risk factors, diagnosis, and treatment approach

  • Ali Amanati,
  • Hamide Barzegar,
  • Gholamreza Pouladfar,
  • Anahita Sanaei Dashti,
  • Mohamad Bagher Abtahi,
  • Bijan Khademi,
  • Mohammad Javad Ashraf,
  • Parisa Badiee,
  • Seyedeh Sedigheh Hamzavi,
  • Ali Kashkooe

DOI
https://doi.org/10.1186/s12879-020-05460-2
Journal volume & issue
Vol. 20, no. 1
pp. 1 – 9

Abstract

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Abstract Background Orbital mucormycosis is a rare but potentially severe and troublesome invasive fungal infection that could be occurred even in healthy individuals. The initial clinical presentation is similar to bacterial pre-septal or septal cellulitis, especially in early stages. Case presentation Herein, we describe the successful management of a series of five cases presenting with orbital mucormycosis in previously healthy children. Conclusions Orbital mucormycosis is extremely rare in healthy children and maybe life-threatening when diagnosis delayed given a similar clinical presentation with bacterial septal cellulitis. Intravenous antifungal therapy with amphotericin B and timely surgical drainage is live-saving.

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