Non-enzymatic roles of human RAD51 at stalled replication forks

Jennifer M. Mason; Yuen-Ling Chan; Ralph W. Weichselbaum; Douglas K. Bishop

doi:10.1038/s41467-019-12297-0

Nature Communications (Sep 2019)

Non-enzymatic roles of human RAD51 at stalled replication forks

Jennifer M. Mason,
Yuen-Ling Chan,
Ralph W. Weichselbaum,
Douglas K. Bishop

Affiliations

Jennifer M. Mason: Department of Radiation and Cellular Oncology, University of Chicago
Yuen-Ling Chan: Department of Radiation and Cellular Oncology, University of Chicago
Ralph W. Weichselbaum: Department of Radiation and Cellular Oncology, University of Chicago
Douglas K. Bishop: Department of Radiation and Cellular Oncology, University of Chicago

DOI: https://doi.org/10.1038/s41467-019-12297-0
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 11

Abstract

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RAD51 has been implicated in replication fork processing and restart in response to replication stress. Here, authors reveal mechanistic aspects of non-enzymatic roles of RAD51 for fork reversal and cooperation with FBH1.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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