Genetics of antibiotic resistance in methicillin-resistant Staphylococcus aureus (MRSA)

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) strains pose a significant threat as common causes of bac­terial infections in hospitals, often resistant to available antibiotics such as daptomycin, vancomycin, and linezolid. The continuous emergence of new MRSA isolates with no effective treatment options underscores a real threat to health among humans and animals, and the number of effective antibiotic therapies decreases with each pas­sing year. In this review, we provide an overview of the most common genetic mechanisms of resistance to a broad spectrum of antibiotics in methicillin-resistant S. aureus.

Keywords

• staphylococcus aureus
• mrsa
• antibiotic resistance