Journal of Aziz Fatimah Medical and Dental College (Feb 2021)
Frequency of Eosinophilia among Patients of Chronic Obstructive Pulmonary Disease with Acute Exacerbation
Abstract
Objective: To determine the frequency of eosinophilia among patients of chronic obstructive pulmonary disease with acute exacerbation Methodology: This cross-sectional study was carried out at Aziz Fatimah Hospital (AFH), Faisalabad from February 2020-May 2020. Ethical approval was taken from Institutional Ethical Committee of Aziz Fatimah Medical and Dental College. After obtaining informed consent, 135 patients of chronic obstructive pulmonary disease were enrolled by non-probability consecutive sampling technique according to inclusion and exclusion criteria. All the information was collected on predesigned proforma. Blood samples were drawn and sent to the AFH pathology laboratory for determination of eosinophilia. Statistical analysis was performed by SPSS 21. Mean and percentages were determined for continuous and categorical variables respectively. Chi square test was applied for differences in proportions. Results: This study comprised of 135 patients of chronic obstructive pulmonary disease. Out of total participants 48.89% (n=66) were male and 51.11% (n=69) were females. Mean±SD of the age of the study subjects was 56.30±7.01 years. Eosinophilia was found in 39.26% (n=53) patients of chronic obstructive pulmonary disease with acute exacerbation. Conclusion: Eosinophilia is frequently found in patients of chronic obstructive pulmonary disease with acute exacerbation.
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