Copper Resistance Promotes Fitness of Methicillin-Resistant Staphylococcus aureus during Urinary Tract Infection

Panatda Saenkham-Huntsinger; Amanda N. Hyre; Braden S. Hanson; George L. Donati; L. Garry Adams; Chanelle Ryan; Alejandra Londoño; Ahmed M. Moustafa; Paul J. Planet; Sargurunathan Subashchandrabose

doi:10.1128/mBio.02038-21

mBio (Oct 2021)

Copper Resistance Promotes Fitness of Methicillin-Resistant Staphylococcus aureus during Urinary Tract Infection

Panatda Saenkham-Huntsinger,
Amanda N. Hyre,
Braden S. Hanson,
George L. Donati,
L. Garry Adams,
Chanelle Ryan,
Alejandra Londoño,
Ahmed M. Moustafa,
Paul J. Planet,
Sargurunathan Subashchandrabose

Affiliations

Panatda Saenkham-Huntsinger: Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA
Amanda N. Hyre: Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA
Braden S. Hanson: Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA
George L. Donati: Department of Chemistry, Wake Forest University, Winston-Salem, North Carolina, USA
L. Garry Adams: Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA
Chanelle Ryan: Division of Pediatric Infectious Diseases, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Alejandra Londoño: Department of Pediatrics, Columbia University, New York, New York, USA
Ahmed M. Moustafa: ORCiD; Division of Pediatric Infectious Diseases, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Paul J. Planet: ORCiD; Division of Pediatric Infectious Diseases, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Sargurunathan Subashchandrabose: ORCiD; Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA

DOI: https://doi.org/10.1128/mBio.02038-21
Journal volume & issue: Vol. 12, no. 5

Abstract

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Urinary tract infection (UTI) is an extremely common infectious condition affecting people throughout the world. Increasing antibiotic resistance in pathogens causing UTI threatens our ability to continue to treat patients in the clinics.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal