Medicina (Jul 2024)

A Contemporary Review of Blood Transfusion in Critically Ill Patients

  • Sumeet K. Yadav,
  • Guleid Hussein,
  • Bolun Liu,
  • Nikhil Vojjala,
  • Mohamed Warsame,
  • Mohamad El Labban,
  • Ibtisam Rauf,
  • Mohamed Hassan,
  • Tashfia Zareen,
  • Syed Muhammad Usama,
  • Yaqi Zhang,
  • Shika M. Jain,
  • Salim R. Surani,
  • Pavan Devulapally,
  • Brian Bartlett,
  • Syed Anjum Khan,
  • Nitesh Kumar Jain

DOI
https://doi.org/10.3390/medicina60081247
Journal volume & issue
Vol. 60, no. 8
p. 1247

Abstract

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Blood transfusion is a common therapeutic intervention in hospitalized patients. There are numerous indications for transfusion, including anemia and coagulopathy with deficiency of single or multiple coagulation components such as platelets or coagulation factors. Nevertheless, the practice of transfusion in critically ill patients has been controversial mainly due to a lack of evidence and the need to consider the appropriate clinical context for transfusion. Further, transfusion carries many risk factors that must be balanced with benefits. Therefore, transfusion practice in ICU patients has constantly evolved, and we endeavor to present a contemporary review of transfusion practices in this population guided by clinical trials and expert guidelines.

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